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KMID : 0614620140630010047
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Korean Journal of Gastroenterology
2014 Volume.63 No. 1 p.47 ~ p.50
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Liver Abscess in Advanced Hepatocellular Carcinoma after Sorafenib Treatment
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Shin Seung-Kak
Jung Young-Kul
Yoon Hyun-Hwa
Kwon Oh-Sang
Kim Yun-Soo
Choi Duck-Joo
Kim Ju-Hyeon
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Abstract
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Hepatocellular carcinoma (HCC) is a critical global health issue and the third most common cause of cancer-related deaths worldwide. The majority of patients who present HCC are already at an advanced stage and their tumors are unresectable. Sorafenib is a multi-kinase inhibitor of the vascular endothelial growth factor pathway and was recently introduced as a therapy for advanced HCC. Furthermore, studies have shown that oral sorafenib has beneficial effects on survival. However, many patients experience diverse side effects, and some of these are severe. Liver abscess development has not been previously documented to be associated with sorafenib administration in HCC. Here, we report the case of a HCC patient that developed a liver abscess while being treated with sorafenib.
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KEYWORD
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Sorafenib, Hepatocellular carcinoma, Liver abscess
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